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Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production: a review.

Posted by on in 2015
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Li X1Wang L1Zhen Y2Li S3Xu Y1. 2015. J Anim Sci Biotechnol. 6(1):40. doi: 10.1186/s40104-015-0038-8. eCollection 2015.

  • 1School of Life Science and Technology, Dalian University of Technology, Dalian, 116024 China ; Ministry of Education Center for Food Safety of Animal Origin, Dalian, 116620 China.
  • 2Department of Pharmacy, Dalian Medical University, Dalian, 116044 China.
  • 3Dalian SEM Bio-Engineering Technology Co. Ltd, Dalian, 116620 China.


In recent years, the use of in-feed antibiotics for growth and disease prevention in livestock production has been under severe scrutiny. The use and misuse of in-feed antibiotics has led to problems with drug residues in animal products and increased bacterial resistance. Chicken egg yolk antibodies (IgY) have attracted considerable attention as an alternative to antibiotics to maintain swine health and performance. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of swine diarrhea diseases and speculates on the future of IgY technology. Included are a review of the potential applications of IgY in the control of enteric infections of either bacterial or viral origin such as enterotoxigenic Escherichia coli, Salmonella spp., rotavirus, porcine transmissible gastroenteritis virus, and porcine epidemic diarrhea virus. Some potential obstacles to the adoption of IgY technology are also discussed.


Diarrhea; Disease control; Egg yolk antibodies; IgY; Swine

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