Standing out in the field of IgY Immunotechnology

  • Home
    Home A full collection of all the Research Archive entries.
  • Years
    Years Sort entries by year.
  • Tags
    Tags Displays a list of tags that have been used in the blog.
  • Archives
    Archives Contains a list of research entries that were created previously.

Assessment of the reproducibility of random hexapeptide Peptide library-based protein normalization

Posted by on in 2010
  • Font size: Larger Smaller
  • Hits: 1855
  • Print

Dwivedi RCKrokhin OVCortens JPWilkins JA.,  2010, J Proteome Res. 9:1144-9.

Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Winnipeg MB, Canada, R3E 3P4.

Abstract

The wide dynamic range of proteins in biological samples poses a challenge for the detection of low-abundance proteins. Recently, combinatorial hexapeptide peptide libraries have been suggested as an approach to normalization of proteins in such mixtures. We examined the reproducibility of a commercial hexapeptide ligand library for quantitative and comparative serum proteomic analysis. We also compared this technology with IgY-based affinity depletion.

PMID: 20020779 [PubMed - in process]

Last modified on