Home » Research Archive » 2004 » My Account   

Currencies

Acquiring Maternal Immunoglobulin

E. Sally Ward
Center for Immunology, UT Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390
USA Immunity, 2004, 20: 507-508

Abstract

The isolation of a novel Fc receptor (FcRY) from chicken yolk sac provides insight at the mechanistic level as to how avian maternal immunoglobulin (IgY) is transferred to offspring. This receptor is distinct from its mammalian counterpart and is a phospholipase A2 receptor homolog. Biophysical analyses indicate that FcRY achieves pH-dependent binding to IgY through a conformational change.

Corresponding author. Correspondence: E. Sally Ward, 214 648 1260 (phone), 214 648 1259 (fax)

 
Print This Page